What does Yosemite invest in?

Yosemite invests in Biotech, Drug Discovery, Diagnostics, Digital Health and Healthtech Infrastructure at the pre-seed, seed and series-a stages.

Which geographies does Yosemite focus on?

Yosemite focuses on United States, United Kingdom and International, and is headquartered in United States.

What is Yosemite's typical check size?

Yosemite typically writes checks of $0.5M to $5M.

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Explore: Biotech · Drug Discovery · Diagnostics · Digital Health · Pre-Seed · Seed · Series A

Yosemite

VC$1BCo-investsLeads rounds

Fund Size

$1B

Check Size

$0.5M→$5.0M

Location

🇺🇸United States

Links

Website

Investment Thesis

Oncology-focused venture capital fund investing in companies developing gene therapy, cancer vaccines, radiopharmaceuticals and artificial intelligence for cancer treatment and early detection.

About Yosemite

Yosemite is an oncology-focused venture firm that backs early-stage companies and researchers working to make cancer a manageable or non-lethal disease. It combines traditional venture investing with philanthropic grants to academic scientists, aiming to fund breakthrough science very early and support founders as discoveries move toward commercialization.

Sectors

BiotechDrug DiscoveryDiagnosticsDigital HealthHealthtech Infrastructure

Stages

pre-seedseedSeries A

Geographic focus

United StatesUnited KingdomInternational

Notable Investments

Tune Therapeutics, Chai Discovery, Azalea Therapeutics, Sage Care

Verified 16 May 2026 · Sources: company website, Fusion42 review

Frequently asked questions

What does Yosemite invest in?: Yosemite invests in Biotech, Drug Discovery, Diagnostics, Digital Health and Healthtech Infrastructure at the pre-seed, seed and series-a stages.
Which geographies does Yosemite focus on?: Yosemite focuses on United States, United Kingdom and International, and is headquartered in United States.
What is Yosemite's typical check size?: Yosemite typically writes checks of $0.5M to $5M.